EMD-43652

Single-particle
3.3 Å
EMD-43652
3D View Gallery
Deposition: 07/02/2024
Map released: 05/02/2025
Last modified: 05/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43652

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Kappa opioid receptor:Galphai protein in complex with inverse agonist norBNI, Original map G protein

EMD-43652

Single-particle
3.3 Å
EMD-43652
3D View Gallery
Deposition: 07/02/2024
Map released: 05/02/2025
Last modified: 05/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Kappa opioid receptor in complex with heterotrimeric G protein (Gai/b/g) and inverse agonist norBNI

Deposition Authors: Gati C , Motiwala Z , Tyson AS , Styrpejko D , Han GW , Khan S , Ramos-Gonzalez N , Shenvi R , Majumdar S
Molecular mechanisms of inverse agonism via kappa-opioid receptor-G protein complexes.
Tyson AS , Khan S , Motiwala Z , Han GW , Zhang Z, Ranjbar M, Styrpejko D , Ramos-Gonzalez N , Woo S , Villers K, Landaker D , Kenakin T , Shenvi R , Majumdar S , Gati C
(2025) Nat Chem Biol
PUBMED: 39775170
DOI: doi:10.1038/s41589-024-01812-0
ISSN: 1552-4469