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EMD-43558
Kappa opioid receptor in complex with heterotrimerig Gi protein, bound to inverse agonist GB18
EMD-43558
Composite mapSingle-particle
3.3 Å
Deposition: 31/01/2024Map released: 15/01/2025
Last modified: 13/08/2025
Sample Organism:
Homo sapiens
Sample: Kappa opioid receptor in complex with heterotrimeric G protein (Gai/b/g) and inverse agonist JDTic
Fitted models: 8vvg
Deposition Authors: Gati C
,
Motiwala Z ,
Tyson AS,
Styrpejko D,
Han GW,
Khan S,
Ramos-Gonzalez N ,
Shenvi R ,
Majumdar S
Sample: Kappa opioid receptor in complex with heterotrimeric G protein (Gai/b/g) and inverse agonist JDTic
Fitted models: 8vvg
Deposition Authors: Gati C
,
Motiwala Z ,
Tyson AS,
Styrpejko D,
Han GW,
Khan S,
Ramos-Gonzalez N ,
Shenvi R ,
Majumdar S
Molecular mechanisms of inverse agonism via kappa-opioid receptor-G protein complexes.
Tyson AS,
Khan S,
Motiwala Z ,
Han GW,
Zhang Z,
Ranjbar M,
Styrpejko D,
Ramos-Gonzalez N ,
Woo S ,
Villers K,
Landaker D ,
Kenakin T ,
Shenvi R ,
Majumdar S ,
Gati C
(2025) Nat Chem Biol , 21 , 1046 - 1057
,
Han GW,
Zhang Z,
Ranjbar M,
Styrpejko D,
Ramos-Gonzalez N ,
Woo S ,
Villers K,
Landaker D ,
Kenakin T ,
Shenvi R ,
Majumdar S ,
Gati C
(2025) Nat Chem Biol , 21 , 1046 - 1057
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