Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-43547

Single-particle
2.6 Å
EMD-43547
3D View Gallery
Deposition: 30/01/2024
Map released: 30/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43547
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8vv2 summary report (pdf.gz) Map and 8vv2 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of DHX36 bound to a RNA G-quadruplex derived from the cMyc G-quadruplex, Class 1

EMD-43547

Single-particle
2.6 Å
EMD-43547
3D View Gallery
Deposition: 30/01/2024
Map released: 30/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Bos taurus, Homo sapiens
Sample: Binary Complex of Bos taurus DHX36 bound to a RNA construct derived from the cMyc G-quadruplex
Fitted models: 8vv2

Deposition Authors: Banco MT, Ferre-D'Amare AR

Inter-domain synergy enables both DNA and RNA G-quadruplex unwinding by the DEAH-box helicase DHX36
Banco MT, Paul T, Jiang J, Myong S, Ferre-D'Amare AR
To Be Published