EMD-43546

Single-particle
3.1 Å
EMD-43546
3D View Gallery
Deposition: 30/01/2024
Map released: 11/12/2024
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43546

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vv0 summary report (pdf.gz) Map-8vv0 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of human GABAA receptor pi (GABRP) in complex with GABA

EMD-43546

Single-particle
3.1 Å
EMD-43546
3D View Gallery
Deposition: 30/01/2024
Map released: 11/12/2024
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: pentameric GABAA receptor pi subunit (GABRP) in complex with GABA
Fitted models: 8vv0

Deposition Authors: Wang Y, Klein D
GABA A receptor pi forms channels that stimulate ERK through a G-protein-dependent pathway.
Wang Y, Zhang Y, Li W, Salovska B, Zhang J, Li T, Li H, Liu Y , Kaczmarek LK, Pusztai L, Klein DE
(2025) Mol Cell , 85 , 166 - 176.e5
PUBMED: 39642883
DOI: doi:10.1016/j.molcel.2024.11.016
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: