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EMD-43523

Single-particle
3.9 Å
EMD-43523
3D View Gallery
Deposition: 26/01/2024
Map released: 11/12/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43523
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8vti summary report (pdf.gz) Map and 8vti FULL report (pdf.gz)
EMICSS annotations (xml)

Latrophilin-3 (ADGRL3) HormR and GAIN domains in the context of the holoreceptor

EMD-43523

Single-particle
3.9 Å
EMD-43523
3D View Gallery
Deposition: 26/01/2024
Map released: 11/12/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Latrophilin3/ADGRL3 HormR+GAIN/7TM holoreceptor in complex with synthetic antibody fragment
Fitted models: 8vti

Deposition Authors: Kordon SP , Bandekar SJ , Arac D
Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function.
Kordon SP , Cechova K , Bandekar SJ , Leon K, Dutka P, Siffer G , Kossiakoff AA , Vafabakhsh R , Arac D
(2024) Nat Commun , 15 , 10545 - 10545
PUBMED: 39627215
DOI: doi:10.1038/s41467-024-54836-4
ISSN: 2041-1723