EMD-43523

Single-particle
3.9 Å
EMD-43523
3D View Gallery
Deposition: 26/01/2024
Map released: 11/12/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43523

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vti summary report (pdf.gz) Map-8vti FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Latrophilin-3 (ADGRL3) HormR and GAIN domains in the context of the holoreceptor

EMD-43523

Single-particle
3.9 Å
EMD-43523
3D View Gallery
Deposition: 26/01/2024
Map released: 11/12/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Latrophilin3/ADGRL3 HormR+GAIN/7TM holoreceptor in complex with synthetic antibody fragment
Fitted models: 8vti

Deposition Authors: Kordon SP , Bandekar SJ , Arac D
Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function.
Kordon SP , Cechova K , Bandekar SJ , Leon K, Dutka P, Siffer G , Kossiakoff AA , Vafabakhsh R , Arac D
(2024) Nat Commun , 15 , 10545 - 10545
PUBMED: 39627215
DOI: doi:10.1038/s41467-024-54836-4
ISSN: 2041-1723