EMD-43512

Single-particle
3.07 Å
EMD-43512
3D View Gallery
Deposition: 25/01/2024
Map released: 11/12/2024
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43512

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vsz summary report (pdf.gz) Map-8vsz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of human GABAA receptor pi (GABRP) apo state

EMD-43512

Single-particle
3.07 Å
EMD-43512
3D View Gallery
Deposition: 25/01/2024
Map released: 11/12/2024
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: pentameric GABAA receptor pi subunit (GABRP)
Fitted models: 8vsz

Deposition Authors: Wang Y, Klein D
GABA A receptor pi forms channels that stimulate ERK through a G-protein-dependent pathway.
Wang Y, Zhang Y, Li W, Salovska B, Zhang J, Li T, Li H, Liu Y , Kaczmarek LK, Pusztai L, Klein DE
(2025) Mol Cell , 85 , 166 - 176.e5
PUBMED: 39642883
DOI: doi:10.1016/j.molcel.2024.11.016
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: