EMD-43499

Single-particle
2.28 Å
EMD-43499
3D View Gallery
Deposition: 24/01/2024
Map released: 02/10/2024
Last modified: 29/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43499

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vsj summary report (pdf.gz) Map-8vsj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Engineered peptide-specific binder in complex with HLA-DR1/CLIP

EMD-43499

Single-particle
2.28 Å
EMD-43499
3D View Gallery
Deposition: 24/01/2024
Map released: 02/10/2024
Last modified: 29/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Metamycoplasma arthritidis
Sample: Engineered peptide-specific binder in complex with HLA-DR1/CLIP
Fitted models: 8vsj

Deposition Authors: Jude KM , Yang X, Du H, Kassardjian A , Julien J-P, Huang P, Garcia KC
A general system for targeting MHC class II-antigen complex via a single adaptable loop.
Du H, Liu J, Jude KM , Yang X, Li Y, Bell B, Yang H, Kassardjian A , Blackson W , Mobedi A, Parekh U, Parra Sperberg RA, Julien JP , Mellins ED , Garcia KC , Huang PS
(2025) Nat Biotechnol , 43 , 1673 - 1682
PUBMED: 39672953
DOI: doi:10.1038/s41587-024-02466-y
ISSN: 1087-0156
ASTM: NABIF9