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EMD-43497
Cryo-EM structure of human CD45 extracellular region in complex with adenoviral protein E3/49K
EMD-43497
Single-particle3.8 Å
Deposition: 23/01/2024Map released: 06/11/2024
Last modified: 21/05/2025
Sample Organism:
Homo sapiens,
Human adenovirus 19a
Sample: Complex of extracellular domain od human CD45 and extracellular domain of adenoviral protein E3/49K
Fitted models: 8vse
Deposition Authors: Borowska MT
,
Caveney NA ,
Jude KM ,
Garcia KC
Sample: Complex of extracellular domain od human CD45 and extracellular domain of adenoviral protein E3/49K
Fitted models: 8vse
Deposition Authors: Borowska MT
,
Caveney NA ,
Jude KM ,
Garcia KC
Orientation-dependent CD45 inhibition with viral and engineered ligands.
Borowska MT ,
Liu LD ,
Caveney NA ,
Jude KM ,
Kim WJ,
Masubuchi T ,
Hui E ,
Majzner RG ,
Garcia KC
(2024) Sci Immunol , 9 , eadp0707 - eadp0707
,
Liu LD ,
Caveney NA ,
Jude KM ,
Kim WJ,
Masubuchi T ,
Hui E ,
Majzner RG ,
Garcia KC
(2024) Sci Immunol , 9 , eadp0707 - eadp0707
Grant Support:
- Howard Hughes Medical Institute (HHMI): (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): RO1-AI103867 (United States)
- Ludwig Institute for Cancer Research (LICR): (United States)