EMD-43495

Single-particle
3.1 Å
EMD-43495
3D View Gallery
Deposition: 23/01/2024
Map released: 11/09/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43495

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

avb8/L-TGF-b1/GARP focused on avb8

EMD-43495

Single-particle
3.1 Å
EMD-43495
3D View Gallery
Deposition: 23/01/2024
Map released: 11/09/2024
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: avb8/L-TGF-b1/GARP complex

Deposition Authors: Jin M , Cheng Y, Nishimura SL
Dynamic allostery drives autocrine and paracrine TGF-beta signaling.
Jin M , Seed RI, Cai G, Shing T, Wang L, Ito S, Cormier A, Wankowicz SA, Jespersen JM, Baron JL, Carey ND, Campbell MG, Yu Z, Tang PK, Cossio P, Wen W, Lou J, Marks J, Nishimura SL, Cheng Y
(2024) Cell , 187 , 6200 - 6219.e23
PUBMED: 39288764
DOI: doi:10.1016/j.cell.2024.08.036
ISSN: 1097-4172