EMD-43277

Single-particle
3.3 Å
EMD-43277
3D View Gallery
Deposition: 06/01/2024
Map released: 22/01/2025
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43277
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8vj9 summary report (pdf.gz) Map and 8vj9 FULL report (pdf.gz)
EMICSS annotations (xml)

cryoEM structure of human ACKR3 phosphorylated by GRK5 in complex with Arrestin3 variant with the C edge loop from Arrestin2 inserted

EMD-43277

Single-particle
3.3 Å
EMD-43277
3D View Gallery
Deposition: 06/01/2024
Map released: 22/01/2025
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Bos taurus, synthetic construct, Homo sapiens
Sample: human ACKR3 phosphorylated by GRK5 in complex with Arrestin3
Fitted models: 8vj9

Deposition Authors: Chen Q , Tesmer JJG
Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor.
Chen Q , Schafer CT , Mukherjee S , Wang K , Gustavsson M , Fuller JR , Tepper K, Lamme TD , Aydin Y, Agrawal P, Terashi G , Yao XQ, Kihara D , Kossiakoff AA , Handel TM , Tesmer JJG
(2025) Nature , 643 , 280 - 287
PUBMED: 40399676
DOI: doi:10.1038/s41586-025-09024-9
ISSN: 1476-4687
ASTM: NATUAS