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EMD-43166

Single-particle
4.1 Å
EMD-43166
3D View Gallery
Deposition: 18/12/2023
Map released: 05/06/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43166
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ve6 summary report (pdf.gz) Map and 8ve6 FULL report (pdf.gz)
EMICSS annotations (xml)

(Biarylamine-FT2-WT)1(C10A)3-human transthyretin in the frayed conformation

EMD-43166

Single-particle
4.1 Å
EMD-43166
3D View Gallery
Deposition: 18/12/2023
Map released: 05/06/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Transthyretin
Fitted models: 8ve6

Deposition Authors: Basanta B, Nugroho K , Yan N, Kline GM, Tsai FJ, Wu M, Kelly JW , Lander GC
The conformational landscape of human transthyretin revealed by cryo-EM.
Basanta B, Nugroho K , Yan NL, Kline GM, Powers ET , Tsai FJ, Wu M, Hansel-Harris A , Chen JS, Forli S , Kelly JW , Lander GC
(2025) Nat Struct Mol Biol , 32 , 876 - 883
PUBMED: 39843982
DOI: doi:10.1038/s41594-024-01472-7
ISSN: 1545-9985