EMD-43148

Single-particle
3.5 Å
EMD-43148
3D View Gallery
Deposition: 15/12/2023
Map released: 02/10/2024
Last modified: 18/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43148

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vdf summary report (pdf.gz) Map-8vdf FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human monoclonal antibody C7 targeting IT4VAR22 CIDRa1.7 (PfEMP1 A)

EMD-43148

Single-particle
3.5 Å
EMD-43148
3D View Gallery
Deposition: 15/12/2023
Map released: 02/10/2024
Last modified: 18/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Plasmodium falciparum
Sample: Plasmodium falciparum Erythrocyte Membrane Protein 1 complexed with human monoclonal antibody
Fitted models: 8vdf

Deposition Authors: Raghavan SSR , Ward AB
Broadly inhibitory antibodies to severe malaria virulence proteins.
Reyes RA , Raghavan SSR , Hurlburt NK , Introini V , Bol S , Kana IH , Jensen RW, Martinez-Scholze E, Gestal-Mato M , Lopez-Gutierrez B , Sanz S , Bancells C, Fernandez-Quintero ML , Loeffler JR, Ferguson JA, Lee WH , Martin GM, Theander TG , Lusingu JPA, Minja DTR, Ssewanyana I, Feeney ME , Greenhouse B, Ward AB , Bernabeu M , Pancera M , Turner L , Bunnik EM , Lavstsen T
(2024) Nature , 636 , 182 - 189
PUBMED: 39567685
DOI: doi:10.1038/s41586-024-08220-3
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: