EMD-43048
Cryo-EM structure of E. coli FimH lectin domain bound to Fabs 329-2 and 454-3
EMD-43048
Single-particle3.12 Å
Deposition: 07/12/2023Map released: 18/12/2024
Last modified: 04/06/2025
Sample Organism:
Mus musculus,
Escherichia coli
Sample: Ternary complex of E. coli FimH with Fabs 329-2 and 454-3
Fitted models: 8v93
Deposition Authors: Lees JA
,
Han S
Sample: Ternary complex of E. coli FimH with Fabs 329-2 and 454-3
Fitted models: 8v93
Deposition Authors: Lees JA
,
Han S
Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine.
Silmon de Monerri NC ,
Che Y,
Lees JA ,
Jasti J,
Wu H,
Griffor MC,
Kodali S,
Hawkins JC,
Lypowy J,
Ponce C,
Curley K,
Esadze A,
Carcamo J,
McLellan T,
Keeney D,
Illenberger A,
Matsuka YV,
Shanker S,
Chorro L,
Gribenko AV,
Han S,
Anderson AS,
Donald RGK
(2025) PLoS Pathog , 21 , e1012325 - e1012325
,
Che Y,
Lees JA ,
Jasti J,
Wu H,
Griffor MC,
Kodali S,
Hawkins JC,
Lypowy J,
Ponce C,
Curley K,
Esadze A,
Carcamo J,
McLellan T,
Keeney D,
Illenberger A,
Matsuka YV,
Shanker S,
Chorro L,
Gribenko AV,
Han S,
Anderson AS,
Donald RGK
(2025) PLoS Pathog , 21 , e1012325 - e1012325
Grant Support: