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EMD-43032

Single-particle
2.19 Å
EMD-43032
3D View Gallery
Deposition: 05/12/2023
Map released: 21/02/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43032
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8v8a summary report (pdf.gz) Map and 8v8a FULL report (pdf.gz)
EMICSS annotations (xml)

Alpha7-nicotinic acetylcholine receptor time resolved bound to epibatidine and PNU-120596 desensitized intermediate state

EMD-43032

Single-particle
2.19 Å
EMD-43032
3D View Gallery
Deposition: 05/12/2023
Map released: 21/02/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha7-nicotinic acetylcholine receptor time resolved bound to epibatidine and PNU-120596 desensitized intermediate state
Fitted models: 8v8a

Deposition Authors: Burke SM, Noviello CM, Hibbs RE
Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation.
Burke SM, Avstrikova M, Noviello CM, Mukhtasimova N, Changeux JP, Thakur GA, Sine SM, Cecchini M, Hibbs RE
(2024) Cell , 187 , 1160 - 1176.e21
PUBMED: 38382524
DOI: doi:10.1016/j.cell.2024.01.032
ISSN: 1097-4172