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EMD-43014

Single-particle
3.6 Å
EMD-43014
3D View Gallery
Deposition: 04/12/2023
Map released: 17/07/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43014
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8v81 summary report (pdf.gz) Map and 8v81 FULL report (pdf.gz)
EMICSS annotations (xml)

Phosphorylated, ATP-bound, inhibitor 172-bound E1371Q human cystic fibrosis transmembrane conductance regulator

EMD-43014

Single-particle
3.6 Å
EMD-43014
3D View Gallery
Deposition: 04/12/2023
Map released: 17/07/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: E1371Q-CFTR
Fitted models: 8v81

Deposition Authors: Gao X , Hwang T
Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore.
Gao X , Yeh HI , Yang Z, Fan C , Jiang F, Howard RJ , Lindahl E , Kappes JC, Hwang TC
(2024) Nat Commun , 15 , 6668 - 6668
PUBMED: 39107303
DOI: doi:10.1038/s41467-024-50641-1
ISSN: 2041-1723