EMD-43011

Single-particle
3.4 Å
EMD-43011
3D View Gallery
Deposition: 04/12/2023
Map released: 17/07/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43011

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8v7z summary report (pdf.gz) Map-8v7z FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Phosphorylated, ATP-bound, E1371Q human cystic fibrosis transmembrane conductance regulator (E1371Q-CFTR)

EMD-43011

Single-particle
3.4 Å
EMD-43011
3D View Gallery
Deposition: 04/12/2023
Map released: 17/07/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: E1371Q-CFTR
Fitted models: 8v7z

Deposition Authors: Gao X , Hwang T
Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore.
Gao X , Yeh HI , Yang Z, Fan C , Jiang F, Howard RJ , Lindahl E , Kappes JC, Hwang TC
(2024) Nat Commun , 15 , 6668 - 6668
PUBMED: 39107303
DOI: doi:10.1038/s41467-024-50641-1
ISSN: 2041-1723