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EMD-42997

Single-particle
2.59 Å
EMD-42997
3D View Gallery
Deposition: 01/12/2023
Map released: 17/04/2024
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42997
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8v6n summary report (pdf.gz) Map and 8v6n FULL report (pdf.gz)
EMICSS annotations (xml)

Open-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs

EMD-42997

Single-particle
2.59 Å
EMD-42997
3D View Gallery
Deposition: 01/12/2023
Map released: 17/04/2024
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: full-length human TRPV3 in complex with 2-APB
Fitted models: 8v6n

Deposition Authors: Nadezhdin KD , Neuberger A , Sobolevsky AI , Sobolevsky AI
TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Nadezhdin KD , Neuberger A , Khosrof LS , Talyzina IA, Khau J , Yelshanskaya MV , Sobolevsky AI
(2024) Sci Adv , 10 , eadn2453 - eadn2453
PUBMED: 38691614
DOI: doi:10.1126/sciadv.adn2453
ISSN: 2375-2548