Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-42979

Single-particle
4.1 Å
EMD-42979 Deposition: 30/11/2023
Map released: 10/07/2024
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42979

Engaged conformation of the human mitochondrial DNA polymerase gamma bound to DNA

EMD-42979

Single-particle
4.1 Å
EMD-42979 Deposition: 30/11/2023
Map released: 10/07/2024
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of the human mitochondrial DNA Polymerase Gamma (POLG/POLG2 heterotrimer) bound to a DNA fork in an engaged conformation
Fitted models: 8v54

Deposition Authors: Riccio AA, Krahn JM, Bouvette J, Borgnia JM, Copeland WC
Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis.
Riccio AA, Brannon AJ, Krahn JM, Bouvette J, Williams JG, Borgnia MJ, Copeland WC
(2024) Nucleic Acids Res , 52 , 7863 - 7875
PUBMED: 38932681
DOI: doi:10.1093/nar/gkae539
ISSN: 1362-4962
ASTM: NARHAD