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EMD-42947
Cryo-EM structure of the KCa2.2 channel with inhibitor UCL 1684.
EMD-42947
Single-particle3.1 Å
Deposition: 27/11/2023Map released: 23/04/2025
Last modified: 07/05/2025
Sample Organism:
Rattus norvegicus
Sample: Rat KCa2.2 channel in complex with Calmodulin in the presence of calcium.
Fitted models: 8v3g
Deposition Authors: Nam YW
,
Zhang M
Sample: Rat KCa2.2 channel in complex with Calmodulin in the presence of calcium.
Fitted models: 8v3g
Deposition Authors: Nam YW
,
Zhang M
Cryo-EM structures of the small-conductance Ca 2+ -activated K Ca 2.2 channel.
Nam YW ,
Im D ,
Garcia ASC,
Tringides ML,
Nguyen HM,
Liu Y ,
Orfali R ,
Ramanishka A ,
Pintilie G,
Su CC ,
Cui M ,
Logothetis DE ,
Yu EW ,
Wulff H ,
Chandy KG,
Zhang M
(2025) Nat Commun , 16 , 3690 - 3690
,
Im D ,
Garcia ASC,
Tringides ML,
Nguyen HM,
Liu Y ,
Orfali R ,
Ramanishka A ,
Pintilie G,
Su CC ,
Cui M ,
Logothetis DE ,
Yu EW ,
Wulff H ,
Chandy KG,
Zhang M
(2025) Nat Commun , 16 , 3690 - 3690
Grant Support:
- American Heart Association: 23AIREA1039423 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS101182-03 (United States)