Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-42914
Cryo-EM structure of the KCa2.2 channel bound to inhibitor AP14145.
EMD-42914
Single-particle3.1 Å
Deposition: 22/11/2023Map released: 23/04/2025
Last modified: 07/05/2025
Sample Organism:
Rattus norvegicus
Sample: Rat KCa2.2 channel complex with Calmodulin in the presence of calcium
Fitted models: 8v2h
Deposition Authors: Nam YW
,
Zhang M
Sample: Rat KCa2.2 channel complex with Calmodulin in the presence of calcium
Fitted models: 8v2h
Deposition Authors: Nam YW
,
Zhang M
Cryo-EM structures of the small-conductance Ca 2+ -activated K Ca 2.2 channel.
Nam YW ,
Im D ,
Garcia ASC,
Tringides ML,
Nguyen HM,
Liu Y ,
Orfali R ,
Ramanishka A ,
Pintilie G,
Su CC ,
Cui M ,
Logothetis DE ,
Yu EW ,
Wulff H ,
Chandy KG,
Zhang M
(2025) Nat Commun , 16 , 3690 - 3690
,
Im D ,
Garcia ASC,
Tringides ML,
Nguyen HM,
Liu Y ,
Orfali R ,
Ramanishka A ,
Pintilie G,
Su CC ,
Cui M ,
Logothetis DE ,
Yu EW ,
Wulff H ,
Chandy KG,
Zhang M
(2025) Nat Commun , 16 , 3690 - 3690
Grant Support:
- American Heart Association: 23AIREA1039423 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS101182-03 (United States)