EMD-42887

Single-particle
2.7 Å
EMD-42887
3D View Gallery
Deposition: 21/11/2023
Map released: 04/09/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42887

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8v1q summary report (pdf.gz) Map-8v1q FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Herpes simplex virus 1 polymerase holoenzyme bound to DNA in both open/closed conformations

EMD-42887

Single-particle
2.7 Å
EMD-42887
3D View Gallery
Deposition: 21/11/2023
Map released: 04/09/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human alphaherpesvirus 1 strain KOS, synthetic construct
Sample: Herpes simplex virus 1 polymerase holoenzyme UL30:UL42 in complex with template and primer DNA strands
Fitted models: 8v1q

Deposition Authors: Pan J, Abraham J , Coen DM, Shankar S, Yang P, Hogle J
Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Shankar S, Pan J, Yang P, Bian Y, Oroszlan G, Yu Z, Mukherjee P , Filman DJ, Hogle JM, Shekhar M, Coen DM, Abraham J
(2024) Cell , 187 , 5572 - 5586.e15
PUBMED: 39197451
DOI: doi:10.1016/j.cell.2024.07.048
ISSN: 1097-4172