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EMD-42885

Single-particle
2.98 Å
EMD-42885
3D View Gallery
Deposition: 20/11/2023
Map released: 20/11/2024
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42885
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8v1g summary report (pdf.gz) Map and 8v1g FULL report (pdf.gz)
EMICSS annotations (xml)

plasmodium falciparum Niemann-Pick type C1-related protein bound with MMV009108

EMD-42885

Single-particle
2.98 Å
EMD-42885
3D View Gallery
Deposition: 20/11/2023
Map released: 20/11/2024
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Plasmodium falciparum 3D7
Sample: Niemann-Pick type C1-related protein
Fitted models: 8v1g

Deposition Authors: Zhang Z , Lyu M
The Plasmodium falciparum NCR1 transporter is an antimalarial target that exports cholesterol from the parasite's plasma membrane.
Zhang Z , Lyu M , Han X , Bandara S, Cui M , Istvan ES , Geng X , Tringides ML , Gregor WD , Miyagi M , Oberstaller J , Adams JH , Zhang Y , Nieman MT , von Lintig J , Goldberg DE , Yu EW
(2024) Sci Adv , 10 , eadq6651 - eadq6651
PUBMED: 39693420
DOI: doi:10.1126/sciadv.adq6651
ISSN: 2375-2548