EMD-42878

Single-particle
3.81 Å
EMD-42878
3D View Gallery
Deposition: 19/11/2023
Map released: 13/11/2024
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42878

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8v12 summary report (pdf.gz) Map-8v12 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

plasmodium falciparum Niemann-Pick type C1-related protein form II

EMD-42878

Single-particle
3.81 Å
EMD-42878
3D View Gallery
Deposition: 19/11/2023
Map released: 13/11/2024
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Plasmodium falciparum 3D7
Sample: Niemann-Pick type C1-related protein
Fitted models: 8v12

Deposition Authors: Zhang Z , Lyu M
The Plasmodium falciparum NCR1 transporter is an antimalarial target that exports cholesterol from the parasite's plasma membrane.
Zhang Z , Lyu M , Han X , Bandara S, Cui M , Istvan ES , Geng X , Tringides ML , Gregor WD , Miyagi M , Oberstaller J , Adams JH , Zhang Y , Nieman MT , von Lintig J , Goldberg DE , Yu EW
(2024) Sci Adv , 10 , eadq6651 - eadq6651
PUBMED: 39693420
DOI: doi:10.1126/sciadv.adq6651
ISSN: 2375-2548