EMD-42841

Single-particle
2.3 Å
EMD-42841
3D View Gallery
Deposition: 15/11/2023
Map released: 21/02/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42841

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8uzj summary report (pdf.gz) Map-8uzj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Alpha7-nicotinic acetylcholine receptor bound to epibatidine and ivermectin

EMD-42841

Single-particle
2.3 Å
EMD-42841
3D View Gallery
Deposition: 15/11/2023
Map released: 21/02/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha7-nicotinic acetylcholine receptor bound to epibatidine and ivermectin
Fitted models: 8uzj

Deposition Authors: Burke SM, Noviello CM, Hibbs RE
Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation.
Burke SM, Avstrikova M, Noviello CM, Mukhtasimova N, Changeux JP, Thakur GA, Sine SM, Cecchini M, Hibbs RE
(2024) Cell , 187 , 1160 - 1176.e21
PUBMED: 38382524
DOI: doi:10.1016/j.cell.2024.01.032
ISSN: 1097-4172