EMD-42768

Single-particle
3.12 Å
EMD-42768
3D View Gallery
Deposition: 09/11/2023
Map released: 22/11/2023
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42768

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8uxl summary report (pdf.gz) Map-8uxl FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin

EMD-42768

Single-particle
3.12 Å
EMD-42768
3D View Gallery
Deposition: 09/11/2023
Map released: 22/11/2023
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of RyR2-R420W, Calstabin-2, and Calmodulin
Fitted models: 8uxl

Deposition Authors: Miotto MC , Marks AR
Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Miotto MC , Reiken S, Wronska A , Yuan Q, Dridi H , Liu Y, Weninger G , Tchagou C, Marks AR
(2024) Nat Commun , 15 , 8080 - 8080
PUBMED: 39278969
DOI: doi:10.1038/s41467-024-51791-y
ISSN: 2041-1723