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EMD-42721

Single-particle
2.9 Å
EMD-42721 Deposition: 09/11/2023
Map released: 09/07/2025
Last modified: 27/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42721

E. coli 70S ribosome with unmodified P/E-tRNAPro(GGG) bound to slippery P-site CCC-C codon

EMD-42721

Single-particle
2.9 Å
EMD-42721 Deposition: 09/11/2023
Map released: 09/07/2025
Last modified: 27/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli
Sample: Ribosomal complex with mRNA and P/E-tRNA
Fitted models: 8uxb

Deposition Authors: Kimbrough EM, Dunham CM , Nguyen HA
An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting.
Kimbrough EM, Nguyen HA, Li H , Mattingly JM , Bailey NA , Ning W, Gamper H, Hou YM , Gonzalez RL , Dunham CM
(2025) Nat Commun , 16 , 7392 - 7392
PUBMED: 40789848
DOI: doi:10.1038/s41467-025-62342-4
ISSN: 2041-1723