EMD-42714

Single-particle
3.6 Å
EMD-42714
3D View Gallery
Deposition: 09/11/2023
Map released: 09/07/2025
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42714

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ux8 summary report (pdf.gz) Map-8ux8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

E. coli 70S ribosome with unmodified Lys-tRNAPro(GGG) bound to slippery P-site CCC-C codon in the +1 mRNA reading frame

EMD-42714

Single-particle
3.6 Å
EMD-42714
3D View Gallery
Deposition: 09/11/2023
Map released: 09/07/2025
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli
Sample: Ribosomal complex with mRNA and tRNA in the P site
Fitted models: 8ux8

Deposition Authors: Kimbrough EM, Dunham CM , Nguyen HA
An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting.
Kimbrough EM, Nguyen HA, Li H , Mattingly JM , Bailey NA , Ning W, Gamper H, Hou YM , Gonzalez RL , Dunham CM
(2025) Nat Commun , 16 , 7392 - 7392
PUBMED: 40789848
DOI: doi:10.1038/s41467-025-62342-4
ISSN: 2041-1723