EMD-42603

Single-particle
3.23 Å
EMD-42603
3D View Gallery
Deposition: 02/11/2023
Map released: 21/08/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42603

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8uv2 summary report (pdf.gz) Map-8uv2 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human p97/VCP structure with a triazole inhibitor (NSC799462/hexamer)

EMD-42603

Single-particle
3.23 Å
EMD-42603
3D View Gallery
Deposition: 02/11/2023
Map released: 21/08/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: p97/VCP AAA+ ATPase/NSC799462
Fitted models: 8uv2

Deposition Authors: Nandi P , DeVore K, Chiu P-L
Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors.
Nandi P , DeVore K, Wang F, Li S, Walker JD, Truong TT , LaPorte MG, Wipf P , Schlager H, McCleerey J , Paquette W , Columbres RCA , Gan T, Poh YP, Fromme P, Flint AJ, Wolf M, Huryn DM, Chou TF , Chiu PL
(2024) Commun Chem , 7 , 177 - 177
PUBMED: 39122922
DOI: doi:10.1038/s42004-024-01267-3
ISSN: 2399-3669