EMD-42587

Single-particle
2.62 Å
EMD-42587
3D View Gallery
Deposition: 01/11/2023
Map released: 26/02/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42587

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8uuj summary report (pdf.gz) Map-8uuj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM Structure of HCA2 DREADD Gi1 in complex with FCH-2296413

EMD-42587

Single-particle
2.62 Å
EMD-42587
3D View Gallery
Deposition: 01/11/2023
Map released: 26/02/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama, Mus musculus
Sample: Mouse HCAD-Gai1 in complex with FCH-2296413
Fitted models: 8uuj

Deposition Authors: Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL
Structure-guided design of a peripherally restricted chemogenetic system.
Kang HJ, Krumm BE, Tassou A, Geron M, DiBerto JF, Kapolka NJ, Gumpper RH, Sakamoto K, Dewran Kocak D, Olsen RHJ, Huang XP, Zhang S, Huang KL, Zaidi SA, Nguyen MT , Jo MJ, Katritch V, Fay JF, Scherrer G, Roth BL
(2024) Cell , 187 , 7433 - 7449.e20
PUBMED: 39631393
DOI: doi:10.1016/j.cell.2024.11.001
ISSN: 1097-4172