EMD-4256

Single-particle
3.56 Å
EMD-4256
3D View Gallery
Deposition: 06/01/2018
Map released: 11/04/2018
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-4256

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6ffc summary report (pdf.gz) Map-6ffc FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of an inhibitor-bound ABC transporter

EMD-4256

Single-particle
3.56 Å
EMD-4256
3D View Gallery
Deposition: 06/01/2018
Map released: 11/04/2018
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Nanodisc-reconstituted ABCG2 in complex with MZ29 inhibitor
Fitted models: 6ffc

Deposition Authors: Jackson SM , Manolaridis I
Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Jackson SM , Manolaridis I , Kowal J , Zechner M, Taylor NMI, Bause M, Bauer S, Bartholomaeus R, Bernhardt G, Koenig B , Buschauer A, Stahlberg H , Altmann KH, Locher KP
(2018) Nat Struct Mol Biol , 25 , 333 - 340
PUBMED: 29610494
DOI: doi:10.1038/s41594-018-0049-1
ISSN: 1545-9985
Grant Support: