Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-42545

Helical reconstruction
3.2 Å
EMD-42545
3D View Gallery
Deposition: 31/10/2023
Map released: 12/06/2024
Last modified: 31/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42545
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8utp summary report (pdf.gz) Map and 8utp FULL report (pdf.gz)
EMICSS annotations (xml)

KIF1A[1-393] - AMP-PNP two-heads-bound state in complex with a microtubule - class T3L1

EMD-42545

Helical reconstruction
3.2 Å
EMD-42545
3D View Gallery
Deposition: 31/10/2023
Map released: 12/06/2024
Last modified: 31/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Sus scrofa, Homo sapiens
Sample: KIF1A - AMP-PNP two-heads-bound state in complex with a microtubule - class T3LS
Fitted models: 8utp

Deposition Authors: Benoit MPMH , Rao L , Asenjo AB , Gennerich A , Sosa H
Cryo-EM unveils kinesin KIF1A's processivity mechanism and the impact of its pathogenic variant P305L.
Benoit MPMH , Rao L , Asenjo AB , Gennerich A , Sosa H
(2024) Nat Commun , 15 , 5530 - 5530
PUBMED: 38956021
DOI: doi:10.1038/s41467-024-48720-4
ISSN: 2041-1723