EMD-42491

Single-particle
4.4 Å
EMD-42491
3D View Gallery
Deposition: 25/10/2023
Map released: 14/08/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42491

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ure summary report (pdf.gz) Map-8ure FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM Structure of Allosterically Switchable De Novo Protein sr312, in Open State with Effector Peptide

EMD-42491

Single-particle
4.4 Å
EMD-42491
3D View Gallery
Deposition: 25/10/2023
Map released: 14/08/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct
Sample: Complex is comprised of 4 sr312 proteins, each sr312 protein is bound to an effector peptide, putting the protein in an open state. Complex is formed with C4 symmetry.
Fitted models: 8ure

Deposition Authors: Weidle C, Skotheim R
De novo design of allosterically switchable protein assemblies.
Pillai A , Idris A, Philomin A , Weidle C, Skotheim R , Leung PJY, Broerman A , Demakis C, Borst AJ , Praetorius F , Baker D
(2024) Nature , 632 , 911 - 920
PUBMED: 39143214
DOI: doi:10.1038/s41586-024-07813-2
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: