EMD-42478

Single-particle
3.6 Å
EMD-42478
3D View Gallery
Deposition: 24/10/2023
Map released: 27/03/2024
Last modified: 24/04/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42478

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8uqv summary report (pdf.gz) Map-8uqv FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Trehalose Synthase (TreS) of Mycobacterium tuberculosis in complex with 6-TreAz compound

EMD-42478

Single-particle
3.6 Å
EMD-42478
3D View Gallery
Deposition: 24/10/2023
Map released: 27/03/2024
Last modified: 24/04/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis
Sample: 6-TreAz bound Trehalose synthase of Mycobacterium tuberculosis
Fitted models: 8uqv

Deposition Authors: Pathirage R , Ronning DR
Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift.
Kalera K, Liu R, Lim J, Pathirage R , Swanson DH, Johnson UG, Stothard AI, Lee JJ, Poston AW, Woodruff PJ , Ronning DR , Eoh H , Swarts BM
(2024) Acs Infect Dis. , 10 , 1391 - 1404
PUBMED: 38485491
DOI: doi:10.1021/acsinfecdis.4c00138
ISSN: 2373-8227