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EMD-4246

Single-particle
3.6 Å
EMD-4246
3D View Gallery
Deposition: 03/01/2018
Map released: 11/04/2018
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-4246
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6feq summary report (pdf.gz) Map and 6feq FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of inhibitor-bound ABCG2

EMD-4246

Single-particle
3.6 Å
EMD-4246
3D View Gallery
Deposition: 03/01/2018
Map released: 11/04/2018
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: inhibitor-bound ABCG2
Fitted models: 6feq

Deposition Authors: Jackson SM , Manolaridis I
Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Jackson SM , Manolaridis I , Kowal J , Zechner M, Taylor NMI, Bause M, Bauer S, Bartholomaeus R, Bernhardt G, Koenig B , Buschauer A, Stahlberg H , Altmann KH, Locher KP
(2018) Nat Struct Mol Biol , 25 , 333 - 340
PUBMED: 29610494
DOI: doi:10.1038/s41594-018-0049-1
ISSN: 1545-9985