EMD-42378

Single-particle
2.9 Å
EMD-42378
3D View Gallery
Deposition: 17/10/2023
Map released: 02/10/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42378

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8umf summary report (pdf.gz) Map-8umf FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of PsCas9 in complex with gRNA and DNA in product state

EMD-42378

Single-particle
2.9 Å
EMD-42378
3D View Gallery
Deposition: 17/10/2023
Map released: 02/10/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Parasutterella secunda
Sample: PsCas9 in with gRNA and dsDNA, product state
Fitted models: 8umf

Deposition Authors: Bravo JPK, Taylor DW

Structure-guided engineering of PsCas9 yields a high fidelity and activity enzyme for in vivo gene editing
Bravo JPK, Taylor DW
To Be Published