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EMD-42245

Single-particle
3.31 Å
EMD-42245
3D View Gallery
Deposition: 06/10/2023
Map released: 01/05/2024
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42245
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8uh3 summary report (pdf.gz) Map and 8uh3 FULL report (pdf.gz)
EMICSS annotations (xml)

Serotonin 1E receptor (5-HT1eR)-Gi1 Complex bound with Setiptiline

EMD-42245

Single-particle
3.31 Å
EMD-42245
3D View Gallery
Deposition: 06/10/2023
Map released: 01/05/2024
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Quaternary complex of serotonin receptor 5-HT1eR with the Gi1 heterotrimer
Fitted models: 8uh3

Deposition Authors: Wacker D , Parpounas AK , Warren AL , Zilberg G
Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R.
Zilberg G , Parpounas AK , Warren AL , Fiorillo B , Provasi D , Filizola M , Wacker D
(2024) Sci Adv , 10 , eadk4855 - eadk4855
PUBMED: 38630816
DOI: doi:10.1126/sciadv.adk4855
ISSN: 2375-2548