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EMD-42185

Single-particle
3.2 Å
EMD-42185
3D View Gallery
Deposition: 03/10/2023
Map released: 14/02/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42185
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8uf7 summary report (pdf.gz) Map and 8uf7 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of POmAb, a Type-I anti-prothrombin antiphospholipid antibody, bound to kringle-1 of human prothrombin

EMD-42185

Single-particle
3.2 Å
EMD-42185
3D View Gallery
Deposition: 03/10/2023
Map released: 14/02/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Complex of Fab fragment of POmAb with human prothrombin
Fitted models: 8uf7

Deposition Authors: Kumar S , Summers B, Basore K , Pozzi N
Cryo-EM structure and functional basis of prothrombin recognition by a type I antiprothrombin antiphospholipid antibody.
Kumar S , Summers B, Basore K , Pengo V, Flaumenhaft R, Pozzi N
(2024) Blood , 143 , 2005 - 2011
PUBMED: 38437497
DOI: doi:10.1182/blood.2023022942
ISSN: 1528-0020