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EMD-42124
Cryo-EM structure of human STEAP1 in complex with AMG 509 Fab
EMD-42124
Single-particle3.0 Å
Deposition: 26/09/2023Map released: 22/11/2023
Last modified: 13/11/2024
Sample Organism:
Homo sapiens
Sample: complex of human STEAP1 with AMG 509 Fab
Fitted models: 8ucd
Deposition Authors: Li F
,
Bailis JM
Sample: complex of human STEAP1 with AMG 509 Fab
Fitted models: 8ucd
Deposition Authors: Li F
,
Bailis JM
AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer.
Nolan-Stevaux O ,
Li C ,
Liang L ,
Zhan J ,
Estrada J ,
Osgood T ,
Li F ,
Zhang H ,
Case R ,
Murawsky CM ,
Estes B ,
Moore GL ,
Bernett MJ ,
Muchhal U ,
Desjarlais JR ,
Staley BK ,
Stevens J ,
Cooke KS ,
Aeffner F ,
Thomas O ,
Stieglmaier J ,
Lee JL ,
Coxon A ,
Bailis JM
(2024) Cancer Discov , 14 , 90 - 103
,
Li C ,
Liang L ,
Zhan J ,
Estrada J ,
Osgood T ,
Li F ,
Zhang H ,
Case R ,
Murawsky CM ,
Estes B ,
Moore GL ,
Bernett MJ ,
Muchhal U ,
Desjarlais JR ,
Staley BK ,
Stevens J ,
Cooke KS ,
Aeffner F ,
Thomas O ,
Stieglmaier J ,
Lee JL ,
Coxon A ,
Bailis JM
(2024) Cancer Discov , 14 , 90 - 103
Grant Support:
- Other private: (United States)