EMD-42116

Single-particle
2.9 Å
EMD-42116
3D View Gallery
Deposition: 25/09/2023
Map released: 31/07/2024
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42116

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8uc7 summary report (pdf.gz) Map-8uc7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

HCN1 complex with propofol

EMD-42116

Single-particle
2.9 Å
EMD-42116
3D View Gallery
Deposition: 25/09/2023
Map released: 31/07/2024
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: HCN1 with propofol
Fitted models: 8uc7

Deposition Authors: Kim ED , Nimigean CM
Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants.
Kim ED , Wu X , Lee S , Tibbs GR , Cunningham KP , Di Zanni E , Perez ME , Goldstein PA , Accardi A , Larsson HP , Nimigean CM
(2024) Nature , 632 , 451 - 459
PUBMED: 39085604
DOI: doi:10.1038/s41586-024-07743-z
ISSN: 1476-4687
ASTM: NATUAS