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EMD-42073

Single-particle
2.97 Å
EMD-42073
3D View Gallery
Deposition: 22/09/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42073
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8uaw summary report (pdf.gz) Map and 8uaw FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of Brucella Abortus Lumazine Synthase (BLS) Engineered with Shiga Toxin II subunit B (Stx2B)

EMD-42073

Single-particle
2.97 Å
EMD-42073
3D View Gallery
Deposition: 22/09/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli O157:H7, Brucella abortus bv. 1 str. 9-941
Sample: Chimeric BLS-Stx2B protein
Fitted models: 8uaw

Deposition Authors: Cristofalo AE, Sharma A, Cerutti ML, Sharma K, Zylberman V, Goldbaum FA, Borgnia MJ, Otero LH
Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against hemolytic uremic syndrome.
Cristofalo AE, Sharma A, Cerutti ML, Sharma K, Melero R, Pardo R, Goldbaum FA, Borgnia M, Zylberman V, Otero LH
(2025) Protein Sci , 34 , e70178 - e70178
PUBMED: 40411437
DOI: doi:10.1002/pro.70178
ISSN: 1469-896X
ASTM: PRCIEI