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EMD-42018
The structure of the PP2A-B56Delta holoenzyme mutant - E197K
EMD-42018
Single-particle3.3 Å
Deposition: 16/09/2023Map released: 10/01/2024
Last modified: 14/05/2025
Sample Organism:
Homo sapiens
Sample: Protein Phosphatase 2A B56 Delta holoenzyme mutant - E197K
Fitted models: 8u89
Deposition Authors: Wu CG
,
Xing Y
Sample: Protein Phosphatase 2A B56 Delta holoenzyme mutant - E197K
Fitted models: 8u89
Deposition Authors: Wu CG
,
Xing Y
B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
Wu CG ,
Balakrishnan VK,
Merrill RA,
Parihar PS ,
Konovolov K,
Chen YC,
Xu Z ,
Wei H ,
Sundaresan R,
Cui Q ,
Wadzinski BE ,
Swingle MR,
Musiyenko A ,
Chung WK ,
Honkanen RE ,
Suzuki A ,
Huang X ,
Strack S ,
Xing Y
(2024) PNAS , 121 , e2310727120 - e2310727120
,
Balakrishnan VK,
Merrill RA,
Parihar PS ,
Konovolov K,
Chen YC,
Xu Z ,
Wei H ,
Sundaresan R,
Cui Q ,
Wadzinski BE ,
Swingle MR,
Musiyenko A ,
Chung WK ,
Honkanen RE ,
Suzuki A ,
Huang X ,
Strack S ,
Xing Y
(2024) PNAS , 121 , e2310727120 - e2310727120
Grant Support: