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EMD-41810
Cryo-EM structure of vaccine-elicited CD4 binding site antibody DH1285 bound to HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env Local Refinement
EMD-41810
Single-particle4.25 Å
Deposition: 31/08/2023Map released: 03/01/2024
Last modified: 04/06/2025
Sample Organism:
Macaca mulatta,
Human immunodeficiency virus 1
Sample: The complex of vaccine elicited CD4 binding site neutralizing antibody DH1285 Fab with CH505M5chimer.6R.SOSIP.664v4.1 Env
Fitted models: 8u1d
Deposition Authors: Thakur B, Stalls VD, Acharya P
Sample: The complex of vaccine elicited CD4 binding site neutralizing antibody DH1285 Fab with CH505M5chimer.6R.SOSIP.664v4.1 Env
Fitted models: 8u1d
Deposition Authors: Thakur B, Stalls VD, Acharya P
Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques.
Saunders KO,
Counts J,
Thakur B,
Stalls V,
Edwards R,
Manne K,
Lu X,
Mansouri K,
Chen Y,
Parks R,
Barr M,
Sutherland L,
Bal J,
Havill N,
Chen H,
Machiele E,
Jamieson N 
,
Hora B,
Kopp M,
Janowska K,
Anasti K,
Jiang C,
Van Itallie E,
Venkatayogi S,
Eaton A,
Henderson R,
Barbosa C,
Alam SM,
Santra S,
Weissman D,
Moody MA,
Cain DW,
Tam YK,
Lewis M,
Williams WB,
Wiehe K,
Montefiori DC,
Acharya P,
Haynes BF
(2024) Cell , 187 , 79 - 94.e24
,
Hora B,
Kopp M,
Janowska K,
Anasti K,
Jiang C,
Van Itallie E,
Venkatayogi S,
Eaton A,
Henderson R,
Barbosa C,
Alam SM,
Santra S,
Weissman D,
Moody MA,
Cain DW,
Tam YK,
Lewis M,
Williams WB,
Wiehe K,
Montefiori DC,
Acharya P,
Haynes BF
(2024) Cell , 187 , 79 - 94.e24