EMD-41806

Single-particle
3.7 Å
EMD-41806
3D View Gallery
Deposition: 31/08/2023
Map released: 04/09/2024
Last modified: 26/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41806

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8u1b summary report (pdf.gz) Map-8u1b FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

C-terminal LRRK2 bound to E11 DARPin

EMD-41806

Single-particle
3.7 Å
EMD-41806
3D View Gallery
Deposition: 31/08/2023
Map released: 04/09/2024
Last modified: 26/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: C-terminal LRRK2 bound to E11 DARPin
Fitted models: 8u1b

Deposition Authors: Sanz-Murillo M, Mathea S , Dederer V, Knapp S, Leschziner A
A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2.
Dederer V, Sanz Murillo M , Karasmanis EP , Hatch KS, Chatterjee D, Preuss F , Abdul Azeez KR, Nguyen LV , Galicia C, Dreier B, Pluckthun A , Versees W , Mathea S , Leschziner AE, Reck-Peterson SL, Knapp S
(2024) J Biol Chem , 300 , 107469 - 107469
PUBMED: 38876305
DOI: doi:10.1016/j.jbc.2024.107469
ISSN: 1083-351X
ASTM: JBCHA3
Grant Support: