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EMD-41724
(N3 Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
EMD-41724
Single-particle3.4 Å
Deposition: 25/08/2023Map released: 16/10/2024
Last modified: 16/10/2024
Sample Organism:
Homo sapiens
Sample: cystic fibrosis transmembrane conductance regulator(CFTR)
Deposition Authors: Wang C
,
Singh S ,
Loughlin BJ,
Yang Z,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Rich Z ,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF ,
Cohen BM
Sample: cystic fibrosis transmembrane conductance regulator(CFTR)
Deposition Authors: Wang C
,
Singh S ,
Loughlin BJ,
Yang Z,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Rich Z ,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF ,
Cohen BM
Mechanism of dual pharmacological correction and potentiation of human CFTR
Wang C ,
Yang Z,
Loughlin BJ,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Singh S ,
Rich Z ,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF ,
Cohen BM
To Be Published
,
Yang Z,
Loughlin BJ,
Xu H,
Veit G,
Vorobiev S,
Clarke OB,
Jiang F,
Li Y,
Singh S ,
Rich Z ,
Menten ER,
Grassucci RA,
Wang W,
Mezzell A,
Fu Z,
Wong K,
Wetmore DR,
Sutton RB,
Brouillette CG,
Urbatsch IL,
Kappes JC,
Lukacs GL,
Frank J,
Hunt JF ,
Cohen BM
To Be Published
Grant Support:
- Cystic Fibrosis Foundation: Hunt18G0 (United States)
- Cystic Fibrosis Foundation: Hunt20G0 (United States)
- Cystic Fibrosis Foundation: HUNT13XX0 (United States)
- Cystic Fibrosis Foundation: 004400G222 (United States)
- Cystic Fibrosis Foundation: FRANK16XX0 (United States)
- Cystic Fibrosis Foundation: FRANK18G0 (United States)