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EMD-41655
Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state)
EMD-41655
Single-particle3.1 Å
Deposition: 18/08/2023Map released: 24/01/2024
Last modified: 28/05/2025
Sample Organism:
Saccharomyces cerevisiae,
synthetic construct
Sample: Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state)
Fitted models: 8tvy
Deposition Authors: Sarsam RD
,
Lahiri I
,
Leschziner AE
Sample: Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state)
Fitted models: 8tvy
Deposition Authors: Sarsam RD
,
Lahiri I
,
Leschziner AE
Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Sarsam RD
,
Xu J
,
Lahiri I
,
Gong W
,
Li Q,
Oh J
,
Zhou Z
,
Hou P,
Chong J,
Hao N
,
Li S
,
Wang D
,
Leschziner AE
(2024) PNAS , 121 , e2314245121 - e2314245121
,
Xu J
,
Lahiri I
,
Gong W
,
Li Q,
Oh J
,
Zhou Z
,
Hou P,
Chong J,
Hao N
,
Li S
,
Wang D
,
Leschziner AE
(2024) PNAS , 121 , e2314245121 - e2314245121
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01 GM092895 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35 GM145296 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01 GM102362 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01 GM092895 (United States)
