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EMD-41613
Cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with temsavir, 8ANC195, and 10-1074
EMD-41613
Single-particle2.96 Å
Deposition: 15/08/2023Map released: 08/11/2023
Last modified: 21/05/2025
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: Complex of BG505 SOSIP.664 with temsavir and the antibody Fabs of 8anc195 and 10-1074
Fitted models: 8ttw
Deposition Authors: Tolbert WD
,
Pozharski E,
Pazgier M
Sample: Complex of BG505 SOSIP.664 with temsavir and the antibody Fabs of 8anc195 and 10-1074
Fitted models: 8ttw
Deposition Authors: Tolbert WD
,
Pozharski E,
Pazgier M
Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Prevost J ,
Chen Y ,
Zhou F,
Tolbert WD ,
Gasser R ,
Medjahed H,
Nayrac M ,
Nguyen DN,
Gottumukkala S,
Hessell AJ ,
Rao VB ,
Pozharski E,
Huang RK,
Matthies D ,
Finzi A,
Pazgier M
(2023) Nat Commun , 14 , 6710 - 6710
,
Chen Y ,
Zhou F,
Tolbert WD ,
Gasser R ,
Medjahed H,
Nayrac M ,
Nguyen DN,
Gottumukkala S,
Hessell AJ ,
Rao VB ,
Pozharski E,
Huang RK,
Matthies D ,
Finzi A,
Pazgier M
(2023) Nat Commun , 14 , 6710 - 6710
Grant Support: