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EMD-41582

Single-particle
2.69 Å
EMD-41582
3D View Gallery
Deposition: 09/08/2023
Map released: 16/10/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41582
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8trk summary report (pdf.gz) Map and 8trk FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the rat P2X7 receptor in complex with the allosteric antagonist methyl blue

EMD-41582

Single-particle
2.69 Å
EMD-41582
3D View Gallery
Deposition: 09/08/2023
Map released: 16/10/2024
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus
Sample: Membrane protein
Fitted models: 8trk

Deposition Authors: Oken AC , Ditter IA , Lisi NE , Krishnamurthy I , McCarthy AE, Godsey MH , Mansoor SE
P2X 7 receptors exhibit at least three modes of allosteric antagonism.
Oken AC , Ditter IA , Lisi NE , Krishnamurthy I , Godsey MH , Mansoor SE
(2024) Sci Adv , 10 , eado5084 - eado5084
PUBMED: 39365862
DOI: doi:10.1126/sciadv.ado5084
ISSN: 2375-2548