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EMD-41566

Single-particle
2.9 Å
EMD-41566
3D View Gallery
Deposition: 08/08/2023
Map released: 06/12/2023
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41566
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8tqz summary report (pdf.gz) Map and 8tqz FULL report (pdf.gz)
EMICSS annotations (xml)

Eukaryotic translation initiation factor 2B with a mutation (L516A) in the delta subunit

EMD-41566

Single-particle
2.9 Å
EMD-41566
3D View Gallery
Deposition: 08/08/2023
Map released: 06/12/2023
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Translation initiation factor 2B decamer
Fitted models: 8tqz

Deposition Authors: Wang L , Lawrence R, Sangwan S, Anand A, Shoemaker S, Deal A, Marqusee S , Watler P
A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling.
Lawrence RE , Shoemaker SR, Deal A, Sangwan S, Anand AA, Wang L , Marqusee S , Walter P
(2024) Nat Chem Biol , 20 , 422 - 431
PUBMED: 37945896
DOI: doi:10.1038/s41589-023-01453-9
ISSN: 1552-4469