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EMD-41498
HIV-1 BG505 Env SOSIP in complex with bovine Fab Bess4 and non-human primate Fab RM20A3
EMD-41498
Single-particle3.3 Å
Deposition: 06/08/2023Map released: 07/08/2024
Last modified: 28/05/2025
Sample Organism:
Human immunodeficiency virus 1,
Macaca mulatta,
Bos taurus
Sample: HIV-1 BG505 SOSIP Env in complex with bovine Bess4 Fab and NHP RM20A3 Fab
Fitted models: 8tq1
Deposition Authors: Ozorowski G, Lee WH, Ward AB
Sample: HIV-1 BG505 SOSIP Env in complex with bovine Bess4 Fab and NHP RM20A3 Fab
Fitted models: 8tq1
Deposition Authors: Ozorowski G, Lee WH, Ward AB
Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Altman PX 
,
Ozorowski G,
Stanfield RL,
Haakenson J,
Appel M,
Parren M,
Lee WH,
Sang H,
Woehl J,
Saye-Francisco K,
Sewall LM,
Joyce C,
Song G,
Porter K,
Landais E,
Andrabi R,
Wilson IA,
Ward AB,
Mwangi W,
Smider VV,
Burton DR,
Sok D
(2024) PLoS Pathog , 20 , e1012042 - e1012042
,
Ozorowski G,
Stanfield RL,
Haakenson J,
Appel M,
Parren M,
Lee WH,
Sang H,
Woehl J,
Saye-Francisco K,
Sewall LM,
Joyce C,
Song G,
Porter K,
Landais E,
Andrabi R,
Wilson IA,
Ward AB,
Mwangi W,
Smider VV,
Burton DR,
Sok D
(2024) PLoS Pathog , 20 , e1012042 - e1012042
Grant Support:
- Bill & Melinda Gates Foundation: INV-034657 (United States)