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EMD-41459
Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide
EMD-41459
Single-particle3.52 Å
Deposition: 03/08/2023Map released: 07/08/2024
Last modified: 15/01/2025
Sample Organism:
Human immunodeficiency virus 1,
Macaca mulatta,
Homo sapiens
Sample: Complex between HIV-1 Env BG505 DS-SOSIP and antibody GPZ6-b.01
Fitted models: 8top
Deposition Authors: Zhou T, Morano NC, Roark RS, Kwong PD
,
Xu J
Sample: Complex between HIV-1 Env BG505 DS-SOSIP and antibody GPZ6-b.01
Fitted models: 8top
Deposition Authors: Zhou T, Morano NC, Roark RS, Kwong PD
,
Xu J
Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Wang H,
Cheng C,
Dal Santo JL,
Shen CH,
Bylund T ,
Henry AR,
Howe CA,
Hwang J ,
Morano NC,
Morris DJ ,
Pletnev S,
Roark RS,
Zhou T,
Hansen BT,
Hoyt FH,
Johnston TS,
Wang S,
Zhang B,
Ambrozak DR,
Becker JE,
Bender MF,
Changela A,
Chaudhary R,
Corcoran M,
Corrigan AR,
Foulds KE,
Guo Y ,
Lee M,
Li Y,
Lin BC,
Liu T,
Louder MK,
Mandolesi M,
Mason RD,
McKee K,
Nair V,
O'Dell S,
Olia AS,
Ou L,
Pegu A,
Raju N,
Rawi R,
Roberts-Torres J,
Sarfo EK,
Sastry M,
Schaub AJ,
Schmidt SD,
Schramm CA,
Schwartz CL ,
Smith SC,
Stephens T,
Stuckey J,
Teng IT,
Todd JP,
Tsybovsky Y,
Van Wazer DJ,
Wang S,
Doria-Rose NA,
Fischer ER,
Georgiev IS,
Karlsson Hedestam GB,
Sheng Z,
Woodward RA,
Douek DC,
Koup RA,
Pierson TC ,
Shapiro L,
Shaw GM,
Mascola JR,
Kwong PD
(2024) Cell , 187 , 7214 - 7231.e23
,
Henry AR,
Howe CA,
Hwang J ,
Morano NC,
Morris DJ ,
Pletnev S,
Roark RS,
Zhou T,
Hansen BT,
Hoyt FH,
Johnston TS,
Wang S,
Zhang B,
Ambrozak DR,
Becker JE,
Bender MF,
Changela A,
Chaudhary R,
Corcoran M,
Corrigan AR,
Foulds KE,
Guo Y ,
Lee M,
Li Y,
Lin BC,
Liu T,
Louder MK,
Mandolesi M,
Mason RD,
McKee K,
Nair V,
O'Dell S,
Olia AS,
Ou L,
Pegu A,
Raju N,
Rawi R,
Roberts-Torres J,
Sarfo EK,
Sastry M,
Schaub AJ,
Schmidt SD,
Schramm CA,
Schwartz CL ,
Smith SC,
Stephens T,
Stuckey J,
Teng IT,
Todd JP,
Tsybovsky Y,
Van Wazer DJ,
Wang S,
Doria-Rose NA,
Fischer ER,
Georgiev IS,
Karlsson Hedestam GB,
Sheng Z,
Woodward RA,
Douek DC,
Koup RA,
Pierson TC ,
Shapiro L,
Shaw GM,
Mascola JR,
Kwong PD
(2024) Cell , 187 , 7214 - 7231.e23
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